- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
AM-9074 is a potent activator of glucokinase, which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-9074 had an EC50 value of 160 nM with good solubility, oral bioavailability and acceptable clearance in rodents, and was shown to lower plasma glucose levels.
Glucokinase activator
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CNC(NC1=CC(OC2=CC(OC)=CN=C2)=C([C@H]3CCCOC3)C=N1)=O |
| InChI | 1S/C18H22N4O4/c1-19-18(23)22-17-7-16(26-14-6-13(24-2)8-20-9-14)15(10-21-17)12-4-3-5-25-11-12/h6-10,12H,3-5,11H2,1-2H3,(H2,19,21,22,23)/t12-/m0/s1 |
| InChI key | APSOPISMEDAYTH-LBPRGKRZSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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