Anti-MMP12 Antibody, clone 1O3A4, Rabbit Monoclonal,100UL,SAB5702839-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BM0759
品牌型号 Sigma SAB5702839-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 371-470 of human MMP12 (P39900).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone1O3A4, monoclonal
formliquid
species reactivityhuman, rat
concentration0.5 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
UniProt accession no.P39900
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... MMP12(4321)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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