- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Ramosetron is a tetra hydrobenzimidazole derivative, containing an indole ring. It inhibits colon contraction mediated by serotonin, competitively.
Ramosetron hydrochloride is a potent serotonin 5-HT3 receptor antagonist with higher afinity for the 5-HT3 receptor than other currently available antagonists.
Ramosetron hydrochloride is a potent serotonin 5-HT3 receptor antagonist with higher afinity for the 5-HT3 receptor than other currently available antagonists. Ramosetron is used clinically both as an antiemetic to treat nausea and vomiting following chemotherapy or after surgery, and in treatment of irritable bowel syndrome.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D -36 to -46°, c = 1 in methanol |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 20 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | Cl.[n]1(c2c(c(c1)C(=O)[C@@H]3CCc4nc[nH]c4C3)cccc2)C |
| InChI | 1S/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1 |
| InChI key | XIXYTCLDXQRHJO-RFVHGSKJSA-N |
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¥ 1683.78
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¥ 3152.47
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¥ 6330.00
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¥ 15214.65
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¥ 10277.12
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¥ 2151.46
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¥ 2307.00
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¥ 1783.21
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