- 商品介绍
- 规格参数
- 包装参数
Application
ED50 = 1 ng/ml on A20 cells. Does not require any enhancer, as the modified linker sequence already facilitates the formation of active FasL complexes. rhsSuperFas Ligand™ recognizes its receptor Fas (CD95) of the following species: human, rat, mouse.
Biochem/physiol Actions
Fas ligand has also been shown to be involved in the activation of non-apoptotic pathways including proliferation and NF-κ B activation.
Fas ligand, a protein belonging to the tumor necrosis factor (TNF) family of cytokines, induces apoptosis in cells expressing the cell membrane receptor Fas (CD95/Apo-1).
Legal Information
SuperFas Ligand is a trademark of Alexis Biochemicals Corp.
| biological source | human |
| Quality Level | 200 |
| recombinant | expressed in HEK 293 cells |
| assay | ≥95% (SDS-GE) |
| form | lyophilized powder |
| mol wt | 32 kDa by SDS-PAGE (nonglycosylated form, under reducing conditions), 35 kDa by SDS-PAGE (glycosylated form, under reducing conditions) |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | P48023 |
| storage temp. | −20°C |
| Gene Information | human ... FASLG(356) |
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