- 商品介绍
- 规格参数
- 包装参数
General description
Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, full length [amino acids 1-414 (end)] with C-terminal FLAG-tag, expressed in Sf9 cells via a baculovirus expression system.
Application
Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .
Biochem/physiol Actions
Human Isocitrate Dehydrogenase (IDH1), also known as oxalosuccinate decarboxylase, is a full length amino acid with a C-terminal FLAG-tag and is expressed in Sf9 cells via a baculovirus expression system. IDH1 expression has been correlated with poor survival of non-small cell lung cancer. IDH1 promotes tumor growth .
Physical form
Solution in 45 mM Tris-HCl, 124 mM NaCl, 2.4 mM KCl, 90 μg/ml FLAG peptide, 3 mM DTT, and 10% glycerol at pH 8.0.
| recombinant | expressed in Sf9 cells |
| Quality Level | 200 |
| assay | ≥90% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| mol wt | 47.6 kDa |
| concentration | ≥0.30 mg/mL protein (Bradford) |
| NCBI accession no. | NM_005896 |
| relevant disease(s) | cancer (lung) |
| shipped in | dry ice |
| storage temp. | −70°C |
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¥ 1596.77
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¥ 2290.21
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¥ 5887.85
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¥ 1196.00
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¥ 5014.59
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¥ 4614.63
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¥ 14985.93
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¥ 3704.60
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