Monoclonal Anti-RNASEH1 antibody produced in mouse，100UG，WH0246243M1-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Ribonuclease H1 (RNASEH1) is an endonuclease which is expressed in the mitochondria and nucleus. It possesses two domains which aid in binding to nucleic acids. The gene encoding this protein is localized on human chromosome 2p25.

Immunogen

RNASEH1 (NP_002927, 189 a.a. ~ 286 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
AACKAIEQAKTQNINKLVLYTDSMFTINGITNWVQGWKKNGWKTSAGKEVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRLAREGAKQSED

Biochem/physiol Actions

Ribonuclease H1 (RNASEH1) digests the RNA segment in a DNA-RNA hybrid. Mutations in the gene encoding it have been associated with chronic progressive external ophthalmoplegia.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Level	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	5D10, monoclonal
form	buffered aqueous solution
species reactivity	human, rat, mouse
technique(s)	indirect ELISA: suitable,western blot: 1-5 μg/mL
isotype	IgG2aκ
GenBank accession no.	NM_002936
UniProt accession no.	O60930
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... RNASEH1(246243)

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