- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Cell-permeable, potent, highly selective, reversible and SAM-competitive DOT1L inhibitor
Massonianoside B is a cell-permeable, potent, highly selective, reversible and SAM-competitive DOT1L (disruptor of 4 telomeric silencing 1-like) inhibitor that decreases cellular levels of H3K79 methylation and inhibits the MLL fusion target genes HOXA9 and MEIS1 expression. Massonianoside B exhibits anti-leukemic activity. It is metabolically stable in both human and mouse liver microsomes.
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
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¥ 1259.40
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¥ 2019.57
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¥ 3109.49
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¥ 8520.40
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¥ 2883.61
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¥ 2151.46
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¥ 3319.60
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