YM-244769 dihydrochloride,25MG,SML3362-25MG,Sigma

销售价: ¥ 4034.25 / 件
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订货号 0BL8363
品牌型号 Sigma SML3362-25MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Potent and selective inhibitor of Na+/Ca2+ exchange (NCX) acting preferentially at NCX3
YM-244769 hydrochloride is a potent and selective inhibitor of Na+/Ca2+ exchange (NCX) acting preferentially at NCX3. It inhibits the Ca2+ entry mode of NCX more potently than the Ca2+ exit mode. YM-244769 exhibits protection in various hypoxic/ischemic cell injury models with low cell toxicity.


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
storage conditiondesiccated
color white to pink
solubilityDMSO: 2 mg/mL, clear
storage temp.-10 to -25°C
SMILES stringO=C(C1=CC=C(OC2=CC=C(OCC3=CC=CC(F)=C3)C=C2)N=C1)NCC4=CC=CC(N)=C4
InChI1S/C26H22FN3O3/c27-21-5-1-4-19(13-21)17-32-23-8-10-24(11-9-23)33-25-12-7-20(16-29-25)26(31)30-15-18-3-2-6-22(28)14-18/h1-14,16H,15,17,28H2,(H,30,31)
InChI keyJZMLHJRKSJXARY-UHFFFAOYSA-N
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