- 商品介绍
- 规格参数
- 包装参数
General description
The kirsten rat sarcoma-2 virus oncogene (KRAS) gene is mapped to human chromosome 12p12.1 and belongs to the family of Ras genes. The protein encoded is a small guanosine nucleotide-bound GTPases belonging.
Immunogen
KRAS purified recombinant protein
Biochem/physiol Actions
Mutation in the KRAS gene causes non small-cell lung cancer and promotes tumor initiation, progression and metastasis. Altered KRAS gene also offers resistance to chemotherapy. It is involved in the signal transduction between epidermal growth factor receptor (EGFR) to the nucleus.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Level | 200 |
| conjugate | unconjugated |
| antibody form | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| clone | KRAS-A582, monoclonal |
| form | aqueous solution |
| mol wt | antigen predicted mol wt 27.9 kDa |
| species reactivity | human |
| technique(s) | western blot: suitable using 5-10ug/ml using HEK-293 cells expressing KRAS |
| isotype | IgG1 |
| UniProt accession no. | P01116 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... KRAS(3845) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |




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