Anti-KRAS antibody, Mouse monoclonal,200UL,SAB4100599-200UL,Sigma

销售价: ¥ 6040.72 / 件
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订货号 0BL7172
品牌型号 Sigma SAB4100599-200UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The kirsten rat sarcoma-2 virus oncogene (KRAS) gene is mapped to human chromosome 12p12.1 and belongs to the family of Ras genes. The protein encoded is a small guanosine nucleotide-bound GTPases belonging.


Immunogen

KRAS purified recombinant protein


Biochem/physiol Actions

Mutation in the KRAS gene causes non small-cell lung cancer and promotes tumor initiation, progression and metastasis. Altered KRAS gene also offers resistance to chemotherapy. It is involved in the signal transduction between epidermal growth factor receptor (EGFR) to the nucleus.


Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level200
conjugateunconjugated
antibody formpurified from hybridoma cell culture
antibody product typeprimary antibodies
cloneKRAS-A582, monoclonal
formaqueous solution
mol wtantigen predicted mol wt 27.9 kDa
species reactivityhuman
technique(s)western blot: suitable using 5-10ug/ml using HEK-293 cells expressing KRAS
isotypeIgG1
UniProt accession no.P01116
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... KRAS(3845)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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