[KO Validated]Anti-FGFR2 Antibody, clone 0O6A9, Rabbit Monoclonal，100UL，SAB5701962-100UL，Sigma

销售价： ¥ 3636.13 / 件

在线询价

优惠：请询价

订货号： 0BL4058

品牌型号： Sigma SAB5701962-100UL

货期：询货期

最小订货量： 1件

+ -

加入购物车

联系我们

400-920-3909

微信扫一扫，手机采购

精选商品

胰蛋白胨，500g，LP0042B，Oxoid

销售价：询价

加入购物车

商品介绍
规格参数
包装参数

产品介绍 Product Description

General description

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGFR2 (P21802).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
material	colorless
clone	0O6A9, monoclonal
form	liquid
mol wt	145 kDa
species reactivity	human, rat
concentration	1.5 mg/mL
technique(s)	western blot: 1:500 - 1:2000
color	colorless
isotype	IgG
immunogen sequence	MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPR
UniProt accession no.	P21802
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... FGFR2(2263)

长度(mm)
宽度(mm)
高度(mm)
重量(kg)