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- 规格参数
- 包装参数
General description
Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3.
Receptor for VEGFC. Has a tyrosine-protein kinase activity.
Immunogen
Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4.
Application
Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry.
Biochem/physiol Actions
Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | ~160 kDa |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype | IgG |
| immunogen sequence | (L-A-S-E-E) |
| NCBI accession no. | NP_002011.2 |
| UniProt accession no. | P35916 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... FLT4(2324) |
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