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Biochem/physiol Actions
Glycerol phenylbutyrate, a triacylglycerol, is a prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA). Glycerol phenylbutyrate is a nitrogen-binding agent approved for the chronic management of adult and pediatric patients (≥2 years of age) with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.
Prodrug of ER stress inhibitor 4-phenylbutyric acid (PBA); ammonia scavenger
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | oil |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | O=C(OCC(OC(CCCC1=CC=CC=C1)=O)COC(CCCC2=CC=CC=C2)=O)CCCC3=CC=CC=C3 |
| InChI key | ZSDBFLMJVAGKOU-UHFFFAOYSA-N |
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¥ 1563.36
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¥ 4968.78
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¥ 3290.05
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¥ 15214.65
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¥ 3319.60
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¥ 1564.00
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¥ 1156.91
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¥ 4011.97
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¥ 787.34
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¥ 2452.91
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