5-Pregnen-3β-ol-20-one-16α-carbonitrile,100MG,P0543-100MG,Sigma

销售价: ¥ 743.04 / 件
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订货号 0BL2701
品牌型号 Sigma P0543-100MG
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

Application

5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:

  • in the induction of cytochrome P450
  • as pregnane X receptor (PXR) activator in human liver cell lines.


Biochem/physiol Actions

Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.


技术参数 Specifications
biological sourcesynthetic (organic)
Quality Level100
sterilitynon-sterile
assay≥97%
formpowder, crystals or chunks
technique(s)cell culture | mammalian: suitable
solubilitychloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow (with heat)
shipped inambient
storage temp.2-8°C
SMILES stringC[C@@]12[C@](C[C@@H](C#N)[C@@H]2C(C)=O)([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1
InChI1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1
InChI keyVSBHRRMYCDQLJF-ZDNYCOCVSA-N
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