Anti-IL1B (N-terminal) antibody produced in rabbit FITC conjugated,100UL,SAB2108884-100UL,Sigma

销售价: ¥ 3329.53 / 件
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订货号 0BL0643
品牌型号 Sigma SAB2108884-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.


Immunogen

Synthetic peptide directed towards the N terminal region of human IL1B


Physical form

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide


Other Notes

Synthetic peptide located within the following region: MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQL


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
conjugateFITC conjugate
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 17 kDa
species reactivity (predicted by homology)mouse, canine, human, horse, rabbit
concentration0.5 mg/mL
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-8 μg/mL
NCBI accession no.NM_000576
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... IL1B(3553)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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