Idalopirdine,10MG,SML3455-10MG,Sigma

销售价: ¥ 630.57 / 件
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订货号 0BL0428
品牌型号 Sigma SML3455-10MG
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最小订货量 1件
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实验室两箱一柜(超低温冰箱、培养箱、生物安全柜)、离心机
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产品介绍 Product Description

Biochem/physiol Actions

Idalopirdine (Lu AE58054) is an orally available, and potent antagonist of the serotonin 6 (5-HT6) receptor. Idalopirdine has been reported to be highly selective over other G-protein coupled receptors. It has K(d) of 0.2nM for the 5-HT6 receptor with 16-fold selectivity over the 5-HT2A receptor (K(i) 3.2nM) and >100-fold selectivity to all other evaluated targets.
Orally available, selective and potent antagonist of the serotonin 6 (5-HT6) receptor.


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 2 mg/mL, clear
storage temp.-10 to -25°C
SMILES stringFC(F)(C(F)F)COc1cc(ccc1)CNCCc2c3c([nH]c2)cc(cc3)F
InChI1S/C20H19F5N2O/c21-15-4-5-17-14(11-27-18(17)9-15)6-7-26-10-13-2-1-3-16(8-13)28-12-20(24,25)19(22)23/h1-5,8-9,11,19,26-27H,6-7,10,12H2
InChI keyYBAWYTYNMZWMMJ-UHFFFAOYSA-N
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