- 商品介绍
- 规格参数
- 包装参数
Immunogen
The epitope recognized by PLA0108 maps to a region between residue 1100 and the C-terminus (residue 1140) of human damage-specific DNA binding protein 1 using the numbering given in TrEMBL entry Q13289 (GeneID 1642).
Physical form
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
Other Notes
DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human, mouse |
| concentration | 0.2 mg/mL |
| technique(s) | immunohistochemistry: 1:500- 1:2,000,immunoprecipitation (IP): 2-5 μg/mg,western blot: 1:1,000- 1:10,000 |
| accession no. | Q13289 |
| UniProt accession no. | Q16531 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | rabbit ... DDB1(1642) |
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