- 商品介绍
- 规格参数
- 包装参数
General description
MYO7A (myosin VIIA) or HM7A consists of 5 isoleucine-glutamine (IQ) motifs. It is present in retinal epithelial cells. It also interacts with other USH1 (Usher syndrome type 1B) gene products like harmonin and sans. This gene is located on human chromosome 11q13.
Immunogen
MYO7A (NP_000251, 2118 a.a. ~ 2213 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSSGNTYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQMLTAMSKQRGSRS
Biochem/physiol Actions
MYO7A (myosin VIIA) or HM7A is involved in anchoring and holding membrane-bound elements to the actin core of the stereocilium. It acts as a transporter. This protein may participate in the tethering of melanosomes at the root of actin bundles. HM7A is responsible for Usher syndrome type 1B. In mice and humans, alteration in Myo7a causes hereditary deafness.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 1D3, monoclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable |
| isotype | IgG1κ |
| GenBank accession no. | NM_000260 |
| UniProt accession no. | Q13402 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... MYO7A(4647) |
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¥ 2532.00
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