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General description
CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule. It belongs to the L1 family of cell adhesion molecules. The CHL1gene is mapped to human chromosome 3p26.
This ELISA antibody pair detects Human Cell Adhesion Molecule with Homology to L1CAM (L1CAM-2)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
The axon guidance protein encoded by CHL1 (cell adhesion molecule L1 like) gene plays a major role in the guidance of thalamocortical axons and the multiplication and differentiation of neural progenitor cells. CHL1 acts as a tumor-suppressor gene in breast cancer (BC). Mutation in the axon guidance protein results in horizontal gaze palsy with progressive scoliosis (HGPPS). It participates in mental development.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| technique(s) | ELISA: suitable |
| input | sample type plasma sample type cell culture supernatant(s) sample type serum |
| assay range | inter-assay cv: <12% intra-assay cv: <10% |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... CHL1(10752) |
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