Anti-Prion Protein Antibody, clone 3D0J9, Rabbit Monoclonal,100UL,SAB5702623-100UL,Sigma

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订货号 0BN2970
品牌型号 Sigma SAB5702623-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 154-253 of human Prion Protein (P04156).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone3D0J9, monoclonal
formliquid
mol wt 30 kDa
species reactivityrat, human
concentration0.35 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
UniProt accession no.P04156
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PRNP(5621)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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