CD158e (Kir3DL1)-FITC, human,130-123-668,美天旎

销售价: ¥ 4200.21 / 件
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订货号 4SM7930
品牌型号 美天旎 130-123-668
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最小订货量 1件
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产品介绍 Product Description

Clone DX9 recognizes CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4.


Alternative names

KIR3DL1, NKB1, NKB1B, p70


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