CD269 (BCMA)-APC, mouse, REA550, 100 t,130-122-954,美天旎

销售价: ¥ 1475.78 / 件
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订货号 8UG0097
品牌型号 美天旎 130-122-954
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最小订货量 1件
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产品介绍 Product Description

Clone REA550 recognizes the mouse CD269 antigen, which is also known as B cell maturation protein BCMA. CD269 is a member of the TNF receptor superfamily. Its binding to BLyS and APRIL activates transcription factor NF-κB and stimulates IgM production by peripheral blood B cells. A soluble form of BCMA, which inhibits the proliferative activity of APRIL in vitro, decreases tumor cell proliferation in nude mice. CD269 has been detected in immune organs such as spleen, thymus, bone marrow, and heart, as well as at lower levels in kidney and lung and is preferentially expressed in mature B lymphocytes.

Additional information: Clone REA550 displays negligible binding to Fc receptors.


Alternative names

TNFRSF17, Bcm, BCMA, Tnfrsf13, Tnfrsf13a


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