CD162-VioBlue, human, REA319, 30 tests,130-123-617,美天旎

销售价: ¥ 2154.91 / 件
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订货号 7DT7305
品牌型号 美天旎 130-123-617
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最小订货量 1件
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产品介绍 Product Description

Clone REA319 recognizes the human CD162 antigen, a single-pass type I membrane protein which is also known as P-selectin glycoprotein ligand 1 (PSGL-1). CD162 is expressed on neutrophils, monocytes, and most lymphocytes. It is the high affinity receptor for CD62P (P-selectin) on myeloid cells and stimulated T lymphocytes and mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. CD162 is also involved in homeostasis including stem cell homing to the thymus and mature T cell homing to secondary lymphoid organs. It has been found to bind the homeostatic chemokines CCL19 and CCL21 and to support the chemotactic response to these chemokines.

Additional information: Clone REA319 displays negligible binding to Fc receptors.


Alternative names

PSGL-1, SELPLG


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