- 商品介绍
- 规格参数
- 包装参数
Clone REA457 recognizes the mouse Peyer’s patch adhesion molecule 1 (LPAM-1) antigen, a heterodimeric glycoprotein receptor, which is also known as α4β7 integrin. LPAM-1 is a cell surface adhesion molecule involved in lymphocyte trafficking and lymphocyte-cell and matrix interactions. It is expressed on T and B cells. Lymphocytes in spleen and mesenteric lymph nodes have low levels of LPAM-1 expression but can up-regulate their LPAM-1 expression on activation. Cellular ligands include vascular cell adhesion molecule 1 (VCAM-1) and the mucosal addressin cell adhesion molecule 1 (MAdCAM-1), which is present on high endothelial venules of mucosal lymphoid organs. Interaction of LPAM-1 with MAdCAM-1 allows for tissue-specific migration of circulating lymphocytes into the lamina propria and Peyer patches of the gut.
Additional information: Clone REA457 displays negligible binding to Fc receptors.
ITGA4, M290 IEL, Itga4B, Ly69, ITGB7, M290 IEL, CD49d
Technical specifications
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询价
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¥ 659.61
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¥ 774.32
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¥ 560.20
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¥ 3189.90
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¥ 3412.00
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询价
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询价
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询价
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¥ 619.09
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询价
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¥ 904.40
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¥ 1084.32
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¥ 984.94
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询价
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¥ 1079.42
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¥ 1034.27
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¥ 54766.78
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¥ 145427.01
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¥ 18741.69
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