PKCα Antibody, anti-human, APC, REAfinity™,130-132-430,美天旎

销售价: ¥ 4991.21 / 件
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订货号 1YD5979
品牌型号 美天旎 130-132-430
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Clone REA156 recognizes the PKCα antigen regardless of its phosphorylation status. It has been reported to cross-react with PKCβ. PKCα is a serine- and threonine-specific protein kinase that can be activated by calcium and the second messenger diacylglycerol. It plays a role in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKCα is highly expressed in a number of cancer cells where it can acts as a tumor promoter and it is implicated in malignant phenotypes of several tumors such as gliomas and breast cancers. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca2+ handling in myocytes.

Additional information: Clone REA156 displays negligible binding to Fc receptors.


Alternative names

PRKCA, AAG6, PKC-alpha, PRKACA, PKC-A


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