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Product Description
IgM is the first immunoglobulin produced by B cells in the immune response. Surface IgM is expressed on immature and mature B cells, whereas IgM heavy chain is expressed intracellularly in pre–B cells. IgM serves as the antigen receptor of naive B cells and is involved in B cell maturation and complement activation. It reacts with the soluble as well as membrane-bound form of human IgM.
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