CD44 Antibody, anti-human, pure, REAfinity™,130-126-473,美天旎

销售价: ¥ 3177.56 / 件
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订货号 1DV7750
品牌型号 美天旎 130-126-473
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最小订货量 1件
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产品介绍 Product Description

Clone REA690 recognizes the CD44 antigen. CD44 is a marker for many types of cancer stem cells (CSCs), including breast CSCs that possess higher tumorigenicity and metastatic potential, colorectal, pancreatic, and prostate CSCs. In addition, expression was observed in several cancers as well as on carcinoma cell lines. Here, CD44 plays a role in cancer cell migration and matrix adhesion in response to a cellular microenvironment, thus enhancing cellular aggregation and tumor cell growth. CD44 is also expressed on mesodermal cells, such as hematopoietic, fibroblastic, and glial cells.

Additional information: Clone REA690 displays negligible binding to Fc receptors.


Alternative names

CD44s, EMCR III, H-CAM, Pgp-1


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